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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK8
All Species:
40
Human Site:
T414
Identified Species:
67.69
UniProt:
Q86SG6
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86SG6
NP_835464.1
692
74806
T414
T
D
R
G
I
I
M
T
F
G
S
G
S
N
G
Chimpanzee
Pan troglodytes
XP_511801
843
90571
T565
T
D
R
G
I
I
M
T
F
G
S
G
S
N
G
Rhesus Macaque
Macaca mulatta
XP_001106986
781
84378
T503
T
D
R
G
I
I
M
T
F
G
S
G
S
N
G
Dog
Lupus familis
XP_548291
727
78319
T449
T
D
R
G
I
I
M
T
F
G
S
G
S
N
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZR4
698
75246
T420
T
D
R
G
I
I
M
T
F
G
S
G
S
N
G
Rat
Rattus norvegicus
NP_001099274
698
75236
T420
T
D
R
G
I
I
M
T
F
G
S
G
S
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512532
832
89432
T398
S
D
R
G
I
I
M
T
F
G
S
G
S
S
G
Chicken
Gallus gallus
XP_415822
728
79098
T420
T
D
R
G
I
I
M
T
F
G
S
G
S
N
G
Frog
Xenopus laevis
Q7ZZC8
944
104521
G433
E
G
Q
L
Y
S
F
G
S
D
Y
Y
G
C
L
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
T421
T
D
R
G
I
I
M
T
F
G
S
G
S
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_490968
998
111830
A660
S
D
D
G
S
L
I
A
M
G
S
N
K
H
N
Sea Urchin
Strong. purpuratus
XP_001201534
446
48490
S198
P
K
T
H
P
I
L
S
S
R
P
P
T
G
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
S358
R
T
S
E
A
S
K
S
S
R
Y
V
P
V
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
T495
S
P
R
R
M
A
L
T
K
A
P
T
T
N
P
Conservation
Percent
Protein Identity:
100
75.4
87
88.8
N.A.
93.5
93.4
N.A.
68.7
76.9
24.7
73.8
N.A.
N.A.
N.A.
23.2
38.2
Protein Similarity:
100
76.9
87.8
91
N.A.
96.4
95.4
N.A.
74
85.1
39.5
85.2
N.A.
N.A.
N.A.
37.8
50.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
100
0
100
N.A.
N.A.
N.A.
26.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
6.6
100
N.A.
N.A.
N.A.
53.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
N.A.
21.7
Protein Similarity:
N.A.
N.A.
N.A.
44
N.A.
37.1
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
8
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
72
8
0
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
65
0
0
0
0
0
0
% F
% Gly:
0
8
0
72
0
0
0
8
0
72
0
65
8
8
65
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
65
72
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
8
0
8
0
0
0
8
0
0
% K
% Leu:
0
0
0
8
0
8
15
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
8
0
65
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
65
15
% N
% Pro:
8
8
0
0
8
0
0
0
0
0
15
8
8
0
8
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
72
8
0
0
0
0
0
15
0
0
0
0
8
% R
% Ser:
22
0
8
0
8
15
0
15
22
0
72
0
65
8
0
% S
% Thr:
58
8
8
0
0
0
0
72
0
0
0
8
15
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
15
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _